Comments on: Clopidogrel and PPIs – RGH Pharmacy E-Bulletin

By: Robbo

Robbo — Fri, 01 Jan 2010 15:44:32 +0000

Top Post #5 was an RGH bulletin on the effects of PPI's on clopidogrel http://bit.ly/nXEY8

By: Lidia

Lidia — Thu, 06 Aug 2009 04:24:35 +0000

thanks, the artciel is correct after all.

Thanks
Lidia

By: Karin Nyfort-Hansen

Karin Nyfort-Hansen — Thu, 06 Aug 2009 03:30:19 +0000

Hi Lidia,
Thanks for your interest! The statment regarding attenuation of effect is consistent with your interpretation and the rest of the material presented in the E-Bulletin. So I’m not sure whether there is another problem here which I am missing.
Regards,
Karin Nyfort-Hansen
Acting Editor RGH Pharmacy E-Bulletin

By: Robbo

Robbo — Thu, 06 Aug 2009 03:01:50 +0000

G’day Lidia,
I don’t write these great articles. merely assist distribute them. I have passed your comment on

By: Lidia

Lidia — Thu, 06 Aug 2009 01:54:59 +0000

Hi,
Well written article amd I subscribe and enjoy all of these.
However, in this article (Clopidogrel and PPIs), the last summary sentence reads “..ppis… may attenuate the anti-platelet benefits of clopidogrel.”

I thought that PPIs (except pantoprazole) reduce the anti-platelet activity of clopidogrel via inhibition of the CYP2C19 enzyme…
I hope you can verify this via e-mail.
Regards,
Lidia, NPS facilitator at Southcity GP Services

By: Robbo

Robbo — Wed, 01 Apr 2009 00:56:40 +0000

Clopidogrel and PPIs – RGH Pharmacy E-Bulletin A summary of the studies to date http://bit.ly/nXEY8