Antithrombin III (ATIII) is a glycoprotein that circulates in human plasma, and can inactivate thrombin and other proteases of the clotting cascade. Deficiency in ATIII leads to an increased risk of thrombus formation, due to prolongation of the circulation of activated clotting factors. The condition may be either inherited or acquired.
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The RGH E-bulletin is a joint initiative of the Patient Services Section and the Drug and Therapeutics Information Service of the Pharmacy Department, Repatriation General Hospital, Daw Park, South Australia. The RGH Pharmacy E-Bulletin is distributed in electronic format on a weekly basis, and aims to present concise, factual information on issues of current interest in therapeutics, drug safety and cost-effective use of medications.
Editor: Assoc. Prof. Chris Alderman, University of South Australia – Director of Pharmacy, RGH © Pharmacy Department, Repatriation General Hospital, Daw Park, South Australia 5041
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