There are a number of drugs that cause tooth discolouration, which may be categorised as arising either intrinsically or extrinsically. Extrinsic discoloration is defined as stains that occur on the outer surface of the tooth structure and are caused by topical or extrinsic agent, and occur after the tooth has erupted.
Exposure to the drug subsequently causes this type of discolouration. Many drugs have been implicated – for example, cholorhexidine produced tooth discolouration in over half of patients who used a mouthwash or rinse for more than six months.
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Editor: Assoc. Prof. Chris Alderman, University of South Australia – Director of Pharmacy, RGH © Pharmacy Department, Repatriation General Hospital, Daw Park, South Australia 5041.