Migraine is broadly divided into two main categories based on the presence or absence of aura symptoms. For women who experience migraine associated with a fall in serum oestrogen levels (menstrual migraine), the migraine is almost invariably without aura. In comparison, high levels of serum oestrogen appear to be associated with migraine with aura.
While the clinical course of migraine is variable around the time of menopause, the perimenopause is the time of peak prevalence, which is followed by a reduction in prevalence in the early postmenopausal phase. The increase in prevalence of migraine is reported to be predominantly in those women who experience migraine without aura, while the prevalence is largely unchanged in women with pre-existing migraine with aura.
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A joint initiative of the Patient Services Section and the Drug and Therapeutics Information Service of the Pharmacy Department, Repatriation General Hospital, Daw Park, South Australia. The RGH Pharmacy E-Bulletin is distributed in electronic format on a weekly basis, and aims to present concise, factual information on issues of current interest in therapeutics, drug safety and cost-effective use of medications.
Editor: Assoc. Prof. Chris Alderman, University of South Australia – Director of Pharmacy, RGH © Pharmacy Department, Repatriation General Hospital, Daw Park, South Australia 5041.
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