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The latest RGH E-Bulletin is now available. It looks at the topic of drug induced gingival hyperplasia.

Gingival hyperplasia, otherwise known as gingival overgrowth, is a condition characterised by widespread swelling of the gums (gingiva) and can affect speech, mastication, tooth mobility and aesthetics. Among other things, it can be caused by a variety of medications, and was first noticed in 1939 in patients treated with phenytoin.

Some other medications commonly known to cause gingival hyperplasia are the immunosuppressant cyclosporin, and calcium channel blockers frequently used for the treatment of hypertension.

It can be downloaded as a small PDF from the link below.

Drug-induced gingival hyperplasia (145) Volume 35 (10): September 28, 2009

The 2009 RGH E-Bulletins are archived by topic here.

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From the newsletter:

Suboptimal inhaler technique is a major barrier to effectiveness of inhalation therapy. Many patients, particularly the elderly and the very young have difficulty correctly using currently available inhaler devices.

Consequently, there is ongoing research into the development of inhaler devices that are easy to use and provide improved lung deposition. The Respimat® Soft Mist inhaler is a novel, metered-dose device for delivery of inhaled drugs to patients with asthma and chronic obstructive pulmonary disease.

The Respimat® inhaler uses mechanical power from a spring rather than propellants to release a ‘Soft Mist’ which lasts longer and is slower moving than that emitted from a pressurised metered dose inhaler (MDI). As compared to the MDI, which initially releases particles of a relatively large diameter (15 to 20 μm), the Respimat® inhaler releases a high proportion of particles which are respirable (<5μm).

To continue reading the newsletter download it here

A joint initiative of the Patient Services Section and the Drug and Therapeutics Information Service of the Pharmacy Department, Repatriation General Hospital, Daw Park, South Australia. The RGH Pharmacy E-Bulletin is distributed in electronic format on a weekly basis, and aims to present concise, factual information on issues of current interest in therapeutics, drug safety and cost-effective use of medications.
Editor: Assoc. Prof. Chris Alderman, University of South Australia – Director of Pharmacy, RGH © Pharmacy Department, Repatriation General Hospital, Daw Park, South Australia 5041.

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Design Your Own Drug

by Robbo on 01/01/2009

New Year’s Day. I am sure there are more immediate needs you need the “Design Your own Drug” for.
Click on the pic and start designing.

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A new niche company has been formed: HARLOT, specialising in How to Achieve positive Results without actually Lying to Overcome the Truth.

I am sure their services will be much in demand, particularly by the pharmaceutical industry. (Click on the picture to down load the small file.)

This bulletin is produced by the Repatriation General Hospital in Adelaide.

Even their Chief Pharmacist, Chris Alderman has a sense of humour. Here’s a joke he submitted to Auspharm

Pearly Gates

An emergency physician, a psychiatrist, a pharmacist and a hospital administrator all had the misfortune to pass away on the same day. Arriving simultaneously at the Pearly Gates, they were all asked by Saint Peter to plead their cases for entry.

“All of my life I’ve worked with people in extremis”said the ER doctor ­ “I pull them back from death’s door and save them from a premature parting.” “Fair enough” said St Peter, “welcome to the kingdom of heaven!”

“I’ve devoted my career to helping the troubled and disturbed, I’ve been there when troubled folk have needed support” said the psychiatrist. “Well done, you’ve earned your time in paradise eternal, please go through” said St Peter.

“Each day, I’ve tended to the needs of people who’ve needed my help. I’ve supplied their medicines, given them good advice, and I’ve prevented them from being hurt when mistakes are made” said the pharmacist. “You’ve earned your place in heaven, go on in” said St Peter.

“I’ve had to make the tough decisions about how the hospital runs. Who gets treated, what gets funded, and how it all gets paid for” said the administrator, “I’ve done my bit too.”

St Peter looked pensive and eventually replied “Well done – you can come in.” “But you can only stay for three days …”

Boxing Day – The cricket calls

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