
Phytoestrogens are non-steroidal plant compounds that are found in many fruits, vegetables and grains. The most common types of phytoestrogens are coumestans, lignans and isoflavones. These compounds have weak oestrogenic and antioestrogenic activity. The major dietary soy isoflavones, genistein and daidzein, are found in legumes including soybeans, chick peas, lentils and beans. Red clover is another source of isoflavones.
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The 2009 RGH E-Bulletins are archived here.
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A joint initiative of the Patient Services Section and the Drug and Therapeutics Information Service of the Pharmacy Department, Repatriation General Hospital, Daw Park, South Australia. The RGH Pharmacy E-Bulletin is distributed in electronic format on a weekly basis, and aims to present concise, factual information on issues of current interest in therapeutics, drug safety and cost-effective use of medications.
Editor: Assoc. Prof. Chris Alderman, University of South Australia – Director of Pharmacy, RGH © Pharmacy Department, Repatriation General Hospital, Daw Park, South Australia 5041.
Tagged as:
Complementary Medicines,
coumestans,
isoflavones,
lignans,
Menopausal Symptoms,
menopause,
phytoestrogen,
phytooestrogen

The evidence for complementary medicines for the management of menopausal symptoms is still inconclusive. A number of agents have been studied; however the majority of clinical trials were poorly designed. Black cohosh and the phytoestrogens are the agents which have been studied the most. This E-bulletin will focus on black cohosh and a further edition will examine the effects of phytoestrogens
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The 2009 RGH E-Bulletins are archived here.
If you like this post and what else you see on the blog please subscribe by RSS feed (the orange button) or by email. Visit my subscription page.
A joint initiative of the Patient Services Section and the Drug and Therapeutics Information Service of the Pharmacy Department, Repatriation General Hospital, Daw Park, South Australia. The RGH Pharmacy E-Bulletin is distributed in electronic format on a weekly basis, and aims to present concise, factual information on issues of current interest in therapeutics, drug safety and cost-effective use of medications.
Editor: Assoc. Prof. Chris Alderman, University of South Australia – Director of Pharmacy, RGH © Pharmacy Department, Repatriation General Hospital, Daw Park, South Australia 5041.
Tagged as:
Actaea racemosa,
Black cohosh,
Cimicifuga racemosa,
Complementary Medicines,
estrogen,
Menopausal Symptoms,
menopause,
oestrogen,
phytoestrogen,
phytooestrogen,
RGH E-bulletin

Migraine is broadly divided into two main categories based on the presence or absence of aura symptoms. For women who experience migraine associated with a fall in serum oestrogen levels (menstrual migraine), the migraine is almost invariably without aura. In comparison, high levels of serum oestrogen appear to be associated with migraine with aura.
While the clinical course of migraine is variable around the time of menopause, the perimenopause is the time of peak prevalence, which is followed by a reduction in prevalence in the early postmenopausal phase. The increase in prevalence of migraine is reported to be predominantly in those women who experience migraine without aura, while the prevalence is largely unchanged in women with pre-existing migraine with aura.
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The 2009 RGH E-Bulletins are archived here.
If you like this post and what else you see on the blog please subscribe by RSS feed (the orange button) or by email. Visit my subscription page.
A joint initiative of the Patient Services Section and the Drug and Therapeutics Information Service of the Pharmacy Department, Repatriation General Hospital, Daw Park, South Australia. The RGH Pharmacy E-Bulletin is distributed in electronic format on a weekly basis, and aims to present concise, factual information on issues of current interest in therapeutics, drug safety and cost-effective use of medications.
Editor: Assoc. Prof. Chris Alderman, University of South Australia – Director of Pharmacy, RGH © Pharmacy Department, Repatriation General Hospital, Daw Park, South Australia 5041.
Tagged as:
drug Information,
HRT,
menopause,
migraine,
RGH E-bulletin
From the Latest RGH Bulletin:
Women with a history of breast cancer can have more frequent and severe vasomotor symptoms than the general population of women. This is due in part to the use of tamoxifen and aromatase inhibitors. As with all women, the management of vasomotor symptoms and symptoms of vaginal atrophy in women with a history of breast cancer requires an individualised, patient centred multidisciplinary approach, based upon the woman’s expectations and goals of therapy
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The 2009 RGH E-Bulletins are archived by topic here.
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Tagged as:
breast cancer,
menopause,
RGH E-bulletin,
treatment