Gilbert’s syndrome is a hereditary (usually autosomal recessive) condition caused by impaired hepatic bilirubin clearance. Gilbert’s syndrome is present in 5–10% of Western European populations, with one in three of those affected unaware that they are affected. Gilbert’s syndrome is characterised by mild unconjugated non-haemolytic hyperbilirubinaemia.
Diagnosis of the disorder is often made after an incidental finding of isolated hyperbilirubinaemia on routine liver biochemistry testing.
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Editor: Assoc. Prof. Chris Alderman, University of South Australia – Director of Pharmacy, RGH © Pharmacy Department, Repatriation General Hospital, Daw Park, South Australia 5041.
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